14. March 2018

Erosion: CURODONT™ REPAIR protects and remineralizes erosive lesions

Independent Japanese researcher tested in vitro the ability of CURODONT™ REPAIR not only to protect but also to remineralize artificial eroded enamel.

In their publication “Application of the Self-Assembling Peptide P11-4 for Prevention of Acidic Erosion”, Suda et al. evaluate the effect of the CUROLOX® TECHNOLOGY (P11-4) to prevent acid erosion of enamel. Using ultrasonic velocity (UV) measurement as non-destructive method to determine the amount of re-mineralization of the samples, SEM images are used to characterize the morphological changes.

Samples were exposed to a pH-cycling model with 6 cycles per day in orange juice (pH 3.6 for 5 min) followed by immersion in artificial saliva.

After initial erosion of the enamel over 28 days, CURODONT™ REPAIR  was applied once to the test samples. As one test group was exposed to a continued pH cycle for 28 days, a second test group was stored in artificial saliva alone.

Both test groups showed a significant increase in ultrasonic velocity, reaching values close to the untreated, sound enamel. Interestingly the group with continued pH cycling revealed significantly higher UV values than the one test group which was only stored in artificial saliva.

SEM pictures showed remineralization between the enamel rods (yellow arrow in SEM picture).

Based on their results Suda and colleagues concluded that the CUROLOX® TECHNOLOGY may be able to prevent the progress of erosion from acid challenge and even to promote remineralization.

Credentis recommends the CURODONT™ PROTECT gel for protection and remineralization of the enamel surface. It was specially developed to form a stable protective layer on the enamel surface with CUROLOX® TECHNOLOGY and has shown its protective and remineralization potential in previous studies.

The article was published online first in Operative Dentistry. A link to the abstract is here